Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL1900198 | 0.94 | SRC (0.54) | MMP3BCL2L1SRCLTA4HNR1H2 | |
| SCHEMBL6429904 | 0.91 | MMP3 (0.52) | MMP3BCL2L1SRCLTA4HNR1H2 | |
| Phenol SCHEMBL17766342 | 0.90 | SRC (0.54) | SRCLTA4HNR1H2BAXMEN1 | |
| Phenol SCHEMBL28139040 | 0.90 | SRC (0.54) | SRCLTA4HNR1H2BAXMEN1 | |
| Hydroquinone SCHEMBL7949657 | 0.85 | SRC (0.59) | SRCLTA4HNR1H2BAXTDP1 | |
| SCHEMBL846983 | 0.84 | LTA4H (0.58) | SRCLTA4HNR1H2BAXMEN1 | |
| SCHEMBL5667535 | 0.84 | LTA4H (0.58) | SRCLTA4HNR1H2BAXMEN1 | |
| SCHEMBL1159889 | 0.84 | SRC (0.58) | SRCLTA4HMEN1LMNAKMT2A | |
| SCHEMBL14718053 | 0.84 | SRC (0.57) | SRCLTA4HNR1H2BAXMEN1 | |
| SCHEMBL6429907 | 0.83 | SRC (0.55) | MMP3BCL2L1SRCLTA4HNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022122-B2 | Derivatives of pyrimidines as flame retardants | BASF SE (DE) | 2011-09-20 | — | — | US | disclosed |
| EP-2013279-B1 | DERIVATIVES OF PYRIMIDINES AS FLAME RETARDANTS | BASF SE (DE) | 2010-03-31 | — | — | EP | disclosed |
| US-20090131565-A1 | Derivatives of Pyrimidines as Flame Retardants | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
| EP-2013279-A1 | DERIVATIVES OF PYRIMIDINES AS FLAME RETARDANTS | Ciba Holding Inc. (CH) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007128678-A1 | DERIVATIVES OF PYRIMIDINES AS FLAME RETARDANTS | CIBA HOLDING INC. (CH) | 2007-11-15 | — | — | WO | disclosed |