Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252519 | 0.84 | HCAR2 (0.52) | MKNK1MKNK2RAF1POLBALOX5 | |
| SCHEMBL30281191 | 0.83 | CYP11B2 (0.45) | CYP11B1CYP11B2MKNK1MKNK2RAF1 | |
| SCHEMBL9607829 | 0.80 | SMYD3 (0.52) | CYP11B1CYP11B2MKNK1MKNK2RAF1 | |
| SCHEMBL31046827 | 0.80 | SMYD3 (0.52) | CYP11B1CYP11B2MKNK1MKNK2RAF1 | |
| SCHEMBL31369753 | 0.80 | HSD17B10 (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL12545798 | 0.80 | EPHX1 (0.47) | EPHX1POLBL3MBTL1ALOX5 | |
| Hydrochloric Acid SCHEMBL29793528 | 0.79 | SMYD3 (0.51) | CYP11B1CYP11B2MKNK1MKNK2RAF1 | |
| SCHEMBL18340498 | 0.78 | CYP11B2 (0.49) | CYP11B1CYP11B2MKNK1MKNK2RAF1 | |
| SCHEMBL7666563 | 0.78 | CYP11B1 (0.49) | CYP11B1CYP11B2MKNK1MKNK2RAF1 | |
| SCHEMBL509510 | 0.78 | CYP11B2 (0.49) | CYP11B1CYP11B2MKNK1MKNK2RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198017-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Academy of Military Medical Sciences (CN) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022033303-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2022-02-17 | — | — | WO | disclosed |