Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252786 | 0.90 | DHODH (0.51) | DHODHCYP19A1PIK3CAKDM4EALDH1A1 | |
| SCHEMBL24252578 | 0.86 | KDM4E (0.50) | DHODHCYP19A1PIK3CAKDM4EALDH1A1 | |
| SCHEMBL24252576 | 0.86 | CYP19A1 (0.60) | DHODHCYP19A1KDM4EALDH1A1MAPT | |
| SCHEMBL23095125 | 0.85 | TNF (0.52) | DHODHCYP19A1KDM4EALDH1A1MAPT | |
| SCHEMBL24252784 | 0.85 | CYP11B1 (0.62) | DHODHCYP19A1PIK3CAKDM4EALDH1A1 | |
| SCHEMBL24252702 | 0.85 | PIK3CA (0.45) | DHODHCYP19A1PIK3CAKDM4EALDH1A1 | |
| SCHEMBL21099083 | 0.85 | CYP19A1 (0.53) | DHODHCYP19A1PIK3CAKDM4EALDH1A1 | |
| SCHEMBL24252707 | 0.85 | CYP11B1 (0.58) | DHODHCYP19A1PIK3CAKDM4EALDH1A1 | |
| SCHEMBL17598655 | 0.84 | ALDH1A1 (0.50) | DHODHCYP19A1KDM4EALDH1A1MAPT | |
| SCHEMBL19167468 | 0.84 | DHODH (0.51) | DHODHCYP19A1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220052268-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220052268-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT | SLC29A1, NUDT1, SLC29A2 | DHODH 202/4885CYP19A1 2810/4885PIK3CA 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.