SCHEMBL24253361

SCHEMBL24253361

Cc1ccc(CCCC(=O)NCCCCC(N)C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 4/20 0.56
LMNA P02545 2/20 0.52
PKM P14618 1/20 0.52
PLAAT3 P53816 1/20 0.50
PLAAT5 Q96KN8 1/20 0.50
PLAAT2 Q9NWW9 1/20 0.50
PLAAT4 Q9UL19 1/20 0.50
SLC5A1 P13866 1/20 0.50
HDAC3 O15379 2/20 0.49
HDAC4 P56524 2/20 0.49
HDAC1 Q13547 2/20 0.49
HDAC7 Q8WUI4 2/20 0.49
HDAC2 Q92769 2/20 0.49
HDAC10 Q969S8 2/20 0.49
HDAC11 Q96DB2 2/20 0.49
HDAC8 Q9BY41 2/20 0.49
HDAC6 Q9UBN7 2/20 0.49
HDAC9 Q9UKV0 2/20 0.49
HDAC5 Q9UQL6 2/20 0.49
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19011013 1.00 ALB (0.56) ALBLMNAPKMPLAAT3PLAAT5
SCHEMBL25499408 0.96 PKM (0.53) ALBLMNAPKMPLAAT3PLAAT5
SCHEMBL25499313 0.90 ALB (0.57) ALBLMNAPKMPLAAT3PLAAT5
SCHEMBL25499309 0.89 ALB (0.56) ALBLMNAPKMPLAAT3PLAAT5
SCHEMBL25728454 0.88 ALB (0.50) ALBLMNAPKMPLAAT3PLAAT5
SCHEMBL22021344 0.88 PLAAT3 (0.48) ALBPLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL14709065 0.88 PLAAT3 (0.48) ALBLMNAPKMPLAAT3PLAAT5
SCHEMBL19929578 0.88 ALB (0.53) ALBLMNAPKMSLC5A1TSHR
SCHEMBL19929579 0.88 ALB (0.53) ALBLMNAPKMSLC5A1TSHR
SCHEMBL19011014 0.88 ALB (0.68) ALBLMNAPKMSLC5A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739076-B2 Compound or its salt thereof targeting fibroblast activation protein, its preparation methods and its uses thereof INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) 2023-08-29 US disclosed
US-11739076-B2 Compound or its salt thereof targeting fibroblast activation protein, its preparation methods and its uses thereof INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) 2023-08-29 US disclosed
US-20230159495-A1 COMPOUND OR ITS SALT THEREOF TARGETING FIBROBLAST ACTIVATION PROTEIN, ITS PREPARATION METHODS AND ITS USES THEREOF INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) 2023-05-25 US disclosed
US-20230159495-A1 COMPOUND OR ITS SALT THEREOF TARGETING FIBROBLAST ACTIVATION PROTEIN, ITS PREPARATION METHODS AND ITS USES THEREOF INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) 2023-05-25 US disclosed
WO-2022032353-A1 RADIOPHARMACEUTICALS, USES THEREOF, AND METHODS FOR THE PRODUCTION THEREOF Clarity Pharmaceuticals Ltd (AU) 2022-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739076-B2 Compound or its salt thereof targeting fibroblast activation protein, its preparation methods and its uses thereof FIBP, FGFR2, FGFR1 ALB 1815/4885LMNA 2746/4885PKM 4225/4885
US-20230159495-A1 COMPOUND OR ITS SALT THEREOF TARGETING FIBROBLAST ACTIVATION PROTEIN, ITS PREPARATION METHODS AND ITS USES THEREOF FIBP, FGFR2, FGFR1 ALB 1815/4885LMNA 2746/4885PKM 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.