⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253234 | 0.67 | — | — | |
| SCHEMBL24253415 | 0.66 | — | — | |
| SCHEMBL22993425 | 0.61 | F11 (0.31) | — | |
| SCHEMBL21576242 | 0.60 | HPGD (0.32) | — | |
| SCHEMBL22993265 | 0.59 | F11 (0.34) | — | |
| SCHEMBL14701604 | 0.58 | NPC1 (0.34) | — | |
| SCHEMBL23349335 | 0.57 | NPC1 (0.33) | — | |
| SCHEMBL24221667 | 0.57 | NPC1 (0.33) | — | |
| SCHEMBL24253419 | 0.57 | — | — | |
| SCHEMBL25091827 | 0.56 | COMT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250080-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LTD (GB) | 2023-08-10 | — | — | US | disclosed |
| US-11613527-B2 | Enzyme inhibitors | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2023-03-28 | — | — | US | disclosed |
| US-20220048894-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |