⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14925528 | 0.68 | HRH4 (0.33) | — | |
| SCHEMBL24253234 | 0.66 | — | — | |
| SCHEMBL24253419 | 0.66 | — | — | |
| SCHEMBL24253417 | 0.66 | — | — | |
| SCHEMBL23844433 | 0.58 | HRH4 (0.30) | — | |
| SCHEMBL21652588 | 0.57 | MAP4K1 (0.34) | — | |
| SCHEMBL14490303 | 0.56 | WDR5 (0.48) | — | |
| SCHEMBL24549192 | 0.56 | WDR5 (0.33) | — | |
| SCHEMBL12092419 | 0.55 | LMNA (0.47) | — | |
| SCHEMBL6289321 | 0.55 | KMT2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250080-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LTD (GB) | 2023-08-10 | — | — | US | disclosed |
| US-11613527-B2 | Enzyme inhibitors | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2023-03-28 | — | — | US | disclosed |
| US-20220048894-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |