Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21248618 | 0.95 | MAPT (0.62) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL29701304 | 0.93 | MAPT (0.58) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL28542188 | 0.93 | MAPT (0.58) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL28910765 | 0.92 | KDM4E (0.57) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL29701302 | 0.91 | MAPT (0.62) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL598475 | 0.91 | MAPT (0.62) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL28543938 | 0.91 | MAPT (0.62) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL528960 | 0.91 | KDM4E (0.56) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL29701308 | 0.91 | KDM4E (0.56) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL28546877 | 0.91 | KDM4E (0.56) | MAPTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8025901-B2 | Bifunctional-modified hydrogels | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-09-27 | — | — | US | disclosed |
| US-20100209509-A1 | BIFUNCTIONAL-MODIFIED HYDROGELS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-08-19 | — | — | US | disclosed |
| US-7615593-B2 | Comprises interpenetrating polymer network/matrix (of collagen and/or gelatin) modified with endcapped polyalkylene glycol; drug delivery; for incorporation into bandages, surgical and dental wound packing material, diapers and catamenial devices | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-11-10 | — | — | US | disclosed |
| US-20060100369-A1 | Bifunctional-modified hydrogels | KAO WEIYUAN J | 2006-05-11 | — | — | US | disclosed |
| US-20050276858-A1 | Bifunctional-modified hydrogels | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-15 | — | — | US | disclosed |
| EP-1423093-A4 | BIFUNCTIONAL-MODIFIED HYDROGELS | WISCONSIN ALUMNI RES FOUND (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1423093-A2 | BIFUNCTIONAL-MODIFIED HYDROGELS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20030083389-A1 | Bifunctional-modified hydrogels | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-01 | — | — | US | disclosed |
| WO-2002085419-A2 | BIFUNCTIONAL-MODIFIED HYDROGELS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050276858-A1 | Bifunctional-modified hydrogels | PCNA, CDC25B, ALG1 | MAPT 3743/4885MEN1 3207/4885KMT2A 1670/4885 |
| US-20100209509-A1 | BIFUNCTIONAL-MODIFIED HYDROGELS | PCNA, CDC25B, ALG1 | MAPT 3743/4885MEN1 3207/4885KMT2A 1670/4885 |
| US-20060100369-A1 | Bifunctional-modified hydrogels | PCNA, CDC25B, ALG1 | MAPT 3743/4885MEN1 3207/4885KMT2A 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.