SCHEMBL29701302

SCHEMBL29701302

CCCC(=O)OC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.62
KDM4E B2RXH2 3/20 0.62
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
LMNA P02545 2/20 0.62
MPO P05164 1/20 0.62
TSHR P16473 1/20 0.62
BLM P54132 1/20 0.62
PMP22 Q01453 1/20 0.62
HIF1A Q16665 1/20 0.62
TACR1 P25103 2/20 0.60
HTR2A P28223 2/20 0.54
PKM P14618 1/20 0.54
ADRB1 P08588 1/20 0.53
HTR1A P08908 1/20 0.53
ADRA2A P08913 1/20 0.53
SLC6A2 P23975 1/20 0.53
HTR1D P28221 1/20 0.53
HTR1B P28222 1/20 0.53
HTR2C P28335 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598475 1.00 MAPT (0.62) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL28543938 1.00 MAPT (0.62) MAPTKDM4EMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL597758 0.99 MAPT (0.61) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL29701304 0.94 MAPT (0.58) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL28542188 0.94 MAPT (0.58) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL28910765 0.93 KDM4E (0.57) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL528960 0.92 KDM4E (0.56) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL28546877 0.92 KDM4E (0.56) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL29701308 0.92 KDM4E (0.56) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL29701301 0.92 KDM4E (0.56) MAPTKDM4EMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12370161-B2 Composition for treating atopy or pruritus comprising N-acetyl or N-acyl amino acid STEMDR INC. (KR) 2025-07-29 US disclosed
US-20230248682-A1 COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID STEMDR INC. (KR) 2023-08-10 US disclosed
US-20220233485-A1 COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID STEMDR INC. (KR) 2022-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220233485-A1 COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID AADAT, NAT1, AANAT MAPT 1612/4885KDM4E 3852/4885MEN1 4486/4885
US-20230248682-A1 COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID AADAT, NAT1, AANAT MAPT 1612/4885KDM4E 3852/4885MEN1 4486/4885
US-12370161-B2 Composition for treating atopy or pruritus comprising N-acetyl or N-acyl amino acid AADAT, NAT1, AANAT MAPT 1612/4885KDM4E 3852/4885MEN1 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.