SCHEMBL24254039

SCHEMBL24254039

c1ccc2c(c1)Oc1cccc3cccc(c13)-c1ccccc1-2

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.96
ATM Q13315 2/20 0.96
KDM4E B2RXH2 1/20 0.96
TYMS P04818 2/20 0.61
ALDH1A1 P00352 6/20 0.58
HSD17B10 Q99714 6/20 0.58
TSHR P16473 4/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
CASP1 P29466 3/20 0.47
CASP7 P55210 2/20 0.47
CYP3A4 P08684 2/20 0.47
PABPC1 P11940 1/20 0.47
DNMT1 P26358 1/20 0.47
HPGD P15428 4/20 0.46
HIF1A Q16665 2/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 3/20 0.38
CYP2D6 P10635 1/20 0.38
CES2 O00748 1/20 0.38
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29907833 0.98 MAPK1 (1.00) MAPK1ATMKDM4ETYMSALDH1A1
SCHEMBL13309034 0.98 MAPK1 (1.00) MAPK1ATMKDM4ETYMSALDH1A1
SCHEMBL24254100 0.91 MAPK1 (0.87) MAPK1ATMKDM4ETYMSALDH1A1
SCHEMBL13309031 0.82 MAPK1 (0.71) MAPK1ATMKDM4ETYMSALDH1A1
SCHEMBL19537981 0.81 MAPK1 (0.61) MAPK1ATMKDM4ETSHRCYP1A2
SCHEMBL5693983 0.81 MAPK1 (0.61) MAPK1ATMKDM4ETSHRCYP1A2
SCHEMBL12172735 0.79 MAPK1 (0.68) MAPK1ATMKDM4ETYMSALDH1A1
SCHEMBL16376391 0.79 MAPK1 (0.67) MAPK1ATMKDM4ETYMSALDH1A1
SCHEMBL3672396 0.79 MAPK1 (0.67) MAPK1ATMKDM4ETYMSALDH1A1
SCHEMBL16558314 0.79 MAPK1 (0.66) MAPK1ATMKDM4ETYMSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TMEM109, OR10J3, LEF1 MAPK1 482/4885ATM 3442/4885KDM4E 1347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.