Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 12/20 | 0.63 |
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid Methyl Ester SCHEMBL27951057 | 0.91 | VEGFA (0.59) | VEGFAEGLN1LMNAHTTMAPT | |
| SCHEMBL1865127 | 0.89 | VEGFA (0.62) | VEGFAEGLN1LMNAMAPTALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27937883 | 0.89 | VEGFA (0.56) | VEGFAEGLN1LMNAHTTMAPT | |
| Tert-Butyl Formate SCHEMBL27937886 | 0.89 | VEGFA (0.64) | VEGFAEGLN1LMNAHTTMAPT | |
| SCHEMBL1870702 | 0.87 | EGLN1 (0.63) | VEGFAEGLN1LMNAHTTMAPT | |
| SCHEMBL1873562 | 0.85 | VEGFA (0.68) | VEGFAEGLN1LMNAHTTMAPT | |
| SCHEMBL24255673 | 0.85 | VEGFA (0.68) | VEGFAEGLN1LMNAHTTMAPT | |
| SCHEMBL14889521 | 0.83 | VEGFA (0.72) | VEGFAEGLN1LMNAHTTMAPT | |
| SCHEMBL1866444 | 0.83 | VEGFA (0.60) | VEGFAEGLN1LMNAHTTALDH1A1 | |
| SCHEMBL17028838 | 0.82 | VEGFA (0.70) | VEGFAEGLN1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036269-A1 | CRYSTALLINE FORMS OF AN HIF-1α PROLYL HYDROXYLASE INHIBITOR | GB004, INC. (US) | 2022-02-17 | — | — | WO | disclosed |