Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SLC9A1 | P19634 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659389 | 1.00 | RAB9A (0.58) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL19111807 | 0.81 | RAB9A (0.58) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL14489533 | 0.81 | RAB9A (0.58) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL13604201 | 0.78 | RAB9A (0.64) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL23057524 | 0.78 | RAB9A (0.64) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL30493903 | 0.78 | RAB9A (0.55) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL28979849 | 0.77 | RAB9A (0.54) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL24072509 | 0.77 | RAB9A (0.54) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL7227104 | 0.76 | SLC9A1 (0.55) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL221980 | 0.76 | RAB9A (0.53) | RAB9ANPC1L3MBTL1SLC9A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036270-A1 | PHOSPHOLIPID BILAYERS CATALYTICALLY PROMOTE PROTEIN REFOLDING, INHIBIT AND REVERSE PROTEIN AGGREGATE FORMATION, AND METHODS OF TREATING NEURODEGENERATIVE DISEASES USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2022-02-17 | — | — | WO | disclosed |