Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760879 | 0.87 | CYP2D6 (0.58) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL2980810 | 0.82 | CYP2D6 (0.53) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL4433902 | 0.82 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL28978077 | 0.82 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL28314029 | 0.82 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL1164889 | 0.82 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL8232303 | 0.82 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL1863910 | 0.82 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL7455235 | 0.82 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL5898644 | 0.81 | CYP2D6 (0.51) | CYP2D6CYP2C9CYP2C19ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196108-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | The Trustees of Indiana University (US) | 2023-06-21 | — | — | EP | claimed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | claimed |
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2023-08-17 | — | — | US | disclosed |
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2023-08-17 | — | — | US | disclosed |
| EP-4196108-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | The Trustees of Indiana University (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | PGLS, BLVRB, CGAS | CYP2D6 4681/4885CYP2C9 4406/4885CYP2C19 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.