Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258204 | 0.86 | MEN1 (0.42) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL19141920 | 0.84 | DEGS1 (0.43) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL10479698 | 0.84 | DEGS1 (0.43) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL10479693 | 0.84 | DEGS1 (0.43) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL23268276 | 0.82 | KMT2A (0.39) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL3386465 | 0.80 | AKR1C3 (0.50) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL23837641 | 0.78 | NFE2L2 (0.54) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL23600216 | 0.77 | PARP1 (0.45) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL8350575 | 0.77 | MEN1 (0.36) | MEN1KMT2ACES2CES1AKT1 | |
| SCHEMBL21182922 | 0.76 | MEN1 (0.39) | MEN1KMT2ACES2CES1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |