Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30542058 | 1.00 | LMNA (0.71) | LMNAALDH1A1NPC1RAB9AMAOB | |
| SCHEMBL6586386 | 0.89 | NR4A2 (0.64) | LMNAALDH1A1NPC1RAB9ANR4A2 | |
| SCHEMBL10341234 | 0.86 | KDM4E (0.72) | LMNAALDH1A1NPC1RAB9AMAOB | |
| SCHEMBL4510662 | 0.84 | LMNA (0.65) | LMNAALDH1A1NPC1RAB9AMAOB | |
| SCHEMBL10341064 | 0.83 | KDM4E (0.71) | LMNAALDH1A1NPC1RAB9AMAOB | |
| SCHEMBL30542063 | 0.83 | KDM4E (0.71) | LMNAALDH1A1NPC1RAB9AMAOB | |
| SCHEMBL398187 | 0.82 | MAOB (0.75) | LMNAALDH1A1NPC1RAB9AMAOB | |
| SCHEMBL22843746 | 0.82 | NR4A2 (0.59) | LMNANR4A2KMT2A | |
| SCHEMBL29398958 | 0.82 | NR4A2 (0.59) | LMNANR4A2KMT2A | |
| SCHEMBL30421484 | 0.81 | POLB (0.61) | LMNAALDH1A1NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735769-B | Quinolinone alkaloid derivative containing acylhydrazone structure at 3-position and preparation method and application thereof | 太原理工大学 | 2023-02-28 | — | — | CN | claimed |
| CN-113735769-A | Quinolinone alkaloid derivative containing acylhydrazone structure at 3-position and preparation method and application thereof | 太原理工大学 | 2021-12-03 | — | — | CN | claimed |
| CN-113735769-B | Quinolinone alkaloid derivative containing acylhydrazone structure at 3-position and preparation method and application thereof | 太原理工大学 | 2023-02-28 | — | — | CN | disclosed |
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| CN-113735769-A | Quinolinone alkaloid derivative containing acylhydrazone structure at 3-position and preparation method and application thereof | 太原理工大学 | 2021-12-03 | — | — | CN | disclosed |