Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30542058 | 0.89 | LMNA (0.71) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL24254462 | 0.89 | LMNA (0.71) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL1093252 | 0.85 | BRD4 (0.69) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL23940250 | 0.84 | BRD4 (0.71) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL4104715 | 0.83 | ALDH1A1 (0.64) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL28968558 | 0.81 | HDAC1 (0.58) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL23940148 | 0.81 | HDAC1 (0.65) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL2434450 | 0.81 | LMNA (0.68) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL30958431 | 0.81 | LMNA (0.68) | NR4A2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL2174829 | 0.81 | NR4A2 (0.65) | NR4A2LMNAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107082774-A | The derivative of one class containing 1,2,4 nitrogen triazole type skeletons and its preparation method and application | 南京大学 | 2017-08-22 | — | — | CN | claimed |
| US-20230263155-A1 | 5-(1H-INDOL-3-YL)-OXAZOLE, -OXADIAZOLE AND -FURAN DERIVATIVES AS ENHANCERS OF SPERM MOTILITY | SPERMATECH AS (NO) | 2023-08-24 | — | — | US | disclosed |
| CN-107082774-A | The derivative of one class containing 1,2,4 nitrogen triazole type skeletons and its preparation method and application | 南京大学 | 2017-08-22 | — | — | CN | disclosed |
| EP-1183252-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-18 | — | — | EP | disclosed |
| US-6492406-B1 | PROTEIN KINASE C INHIBITORS; ANTIINFLAMMATORY AND IMMUNO-SUPPRESSIVE AGENTS | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |
| EP-1183252-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071537-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263155-A1 | 5-(1H-INDOL-3-YL)-OXAZOLE, -OXADIAZOLE AND -FURAN DERIVATIVES AS ENHANCERS OF SPERM MOTILITY | NR5A1, NR1I3, NR5A2 | NR4A2 70/4885LMNA 1688/4885ALDH1A1 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.