Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672357 | 0.93 | ALDH1A1 (0.60) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL15261978 | 0.89 | TAAR1 (0.54) | ALDH1A1TAAR1MTNR1AMTNR1BMEN1 | |
| SCHEMBL4725563 | 0.88 | TAAR1 (0.60) | ALDH1A1TAAR1MTNR1AMTNR1BMEN1 | |
| SCHEMBL17281 | 0.84 | TAAR1 (0.60) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL31506228 | 0.84 | TAAR1 (0.60) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL17280 | 0.84 | TAAR1 (0.60) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL3573062 | 0.84 | L3MBTL1 (0.52) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL7642003 | 0.84 | MAPK1 (0.62) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL4564004 | 0.84 | MAPK1 (0.52) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL2429158 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851435-B2 | PTGR2 inhibitors and their use | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2023-12-26 | — | — | US | disclosed |
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-09-07 | — | — | US | disclosed |
| WO-2011114148-A1 | 4H- [1, 2, 4] TRIAZOLO [5, 1 -B] PYRIMIDIN-7 -ONE DERIVATIVES AS CCR2B RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2011-09-22 | — | — | WO | disclosed |
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851435-B2 | PTGR2 inhibitors and their use | PTGFR, PTGIR, PTGDR2 | ALDH1A1 1177/4885MAPK1 1084/4885L3MBTL1 4693/4885 |
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | PTGFR, PTGIR, PTGDR2 | ALDH1A1 1177/4885MAPK1 1084/4885L3MBTL1 4693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.