Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | S100A9 | P06702 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980545 | 0.83 | TNNI3K (0.52) | TNNI3KLMNAFFAR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL10153812 | 0.80 | TSHR (0.61) | LMNAFFAR4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12067872 | 0.80 | VCAM1 (0.57) | TNNI3KLMNAALDH1A1MAPTS100A9 | |
| SCHEMBL1813497 | 0.80 | TNNI3K (0.47) | TNNI3KS100A9TSHRMAPK1 | |
| SCHEMBL27878032 | 0.78 | LMNA (0.50) | LMNAALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL8521689 | 0.76 | TNNI3K (0.53) | TNNI3KFFAR4S100A9KIF11 | |
| SCHEMBL2371771 | 0.75 | SMN1; SMN2 (0.63) | LMNAFFAR4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL22460999 | 0.75 | LMNA (0.48) | LMNAFFAR4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10154281 | 0.74 | LMNA (0.71) | LMNAALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL4572470 | 0.74 | SLC6A4 (0.51) | TNNI3KLMNAFFAR4SMN1; SMN2S100A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035804-A1 | SUBSTITUTED 3-AMINO-4-METHYLBENZENESULFONAMIDES AS SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | disclosed |