Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | P4HA1 | P13674 | 3/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM5C | P41229 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604301 | 0.72 | KDM4E (0.44) | P4HA1MIFKDM4EALDH1A1KDM4A | |
| SCHEMBL29687112 | 0.69 | KDM4E (0.41) | P4HA1MIFKDM4EALDH1A1KDM4A | |
| SCHEMBL28318621 | 0.69 | KDM4E (0.41) | P4HA1MIFKDM4EALDH1A1KDM4A | |
| SCHEMBL29712705 | 0.68 | NNMT (0.49) | MGAMNNMTP4HA1P4HTMMIF | |
| SCHEMBL16168388 | 0.68 | NNMT (0.41) | MGAMNNMTP4HA1P4HTMMIF | |
| SCHEMBL25789801 | 0.68 | NNMT (0.49) | MGAMNNMTP4HA1P4HTMMIF | |
| SCHEMBL28617969 | 0.67 | NNMT (0.47) | MGAMNNMTP4HA1P4HTMMIF | |
| SCHEMBL1680658 | 0.67 | NNMT (0.73) | MGAMNNMTP4HA1P4HTMMIF | |
| SCHEMBL29686931 | 0.66 | NNMT (0.40) | MGAMNNMTP4HA1P4HTMMIF | |
| SCHEMBL5306512 | 0.65 | NNMT (0.75) | MGAMNNMTP4HA1P4HTMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012995-B1 | Pharmaceutically active sulfonamide derivatives | MERCK SERONO SA (CH) | 2011-09-06 | — | — | US | disclosed |