⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25083686 | 0.78 | HTT (0.50) | — | |
| SCHEMBL25604633 | 0.70 | — | — | |
| SCHEMBL9852100 | 0.67 | — | — | |
| SCHEMBL24408847 | 0.65 | — | — | |
| SCHEMBL24725742 | 0.65 | — | — | |
| SCHEMBL21387010 | 0.62 | — | — | |
| SCHEMBL25083677 | 0.60 | — | — | |
| SCHEMBL18878948 | 0.60 | ALOX5 (0.33) | — | |
| SCHEMBL14182471 | 0.58 | — | — | |
| SCHEMBL14021897 | 0.58 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |