⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725742 | 0.72 | — | — | |
| SCHEMBL21387010 | 0.69 | — | — | |
| SCHEMBL20755012 | 0.69 | SCN9A (0.32) | — | |
| SCHEMBL24256044 | 0.67 | — | — | |
| SCHEMBL24491025 | 0.66 | RAB9A (0.56) | — | |
| SCHEMBL18878948 | 0.66 | ALOX5 (0.33) | — | |
| SCHEMBL24491092 | 0.65 | GRM1 (0.43) | — | |
| SCHEMBL19681525 | 0.65 | GRM1 (0.38) | — | |
| SCHEMBL14021897 | 0.64 | TSHR (0.36) | — | |
| SCHEMBL14182471 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165957-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-07 | — | — | WO | disclosed |
| US-20230192648-A1 | IMMUNOREGULATORY COMPOUNDS | NIMML INSTITUTE (US) | 2023-06-22 | — | — | US | disclosed |
| CN-113302175-A | Bicyclic compounds | 维瓦斯治疗公司 | 2021-08-24 | — | — | CN | disclosed |
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| US-7371746-B2 | 1,2,4-Thiadiazole compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2008-05-13 | — | — | US | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-0455356-A1 | Substituted 5-amino-1,2,4-thiadiazoles with pharmaceutical activity | LILLY INDUSTRIES LIMITED (GB) | 1991-11-06 | — | — | EP | disclosed |
| EP-0025017-A1 | Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter | CIBA-GEIGY AG (CH) | 1981-03-11 | — | — | EP | disclosed |
| EP-0022245-A2 | Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-01-14 | — | — | EP | disclosed |
| US-4166818-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1979-09-04 | — | — | US | disclosed |
| US-4163048-A | Acylamino-1,2,4-oxadiazole or thiadiazole derivatives as anti-hypersensitivity agents | LILLY INDUSTRIES LIMITED (GB) | 1979-07-31 | — | — | US | disclosed |