⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20321948 | 0.74 | — | — | |
| SCHEMBL20876859 | 0.74 | CCNA2 (0.38) | — | |
| SCHEMBL20322050 | 0.69 | IDO1 (0.36) | — | |
| SCHEMBL9852166 | 0.66 | NPC1 (0.61) | — | |
| SCHEMBL18398869 | 0.64 | — | — | |
| SCHEMBL10939231 | 0.63 | SCN9A (0.59) | — | |
| SCHEMBL5172686 | 0.62 | — | — | |
| SCHEMBL183472 | 0.62 | LMNA (0.52) | — | |
| SCHEMBL7076660 | 0.62 | LMNA (0.58) | — | |
| SCHEMBL367014 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |