SCHEMBL24256576

SCHEMBL24256576

CC(=O)CCNC(=O)CCNC(=O)CCNC(=O)[C@H](N)CSC(C)C

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TERT O14746 3/20 0.36
ALDH1A1 P00352 1/20 0.35
DPP7 Q9UHL4 2/20 0.34
METAP2 P50579 1/20 0.33
METAP1 P53582 1/20 0.33
RRM1 P23921 1/20 0.32
ECE1 P42892 1/20 0.32
TLR2 O60603 1/20 0.32
NAMPT P43490 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25868295 0.87 TERT (0.36) TERTALDH1A1DPP7METAP2METAP1
SCHEMBL25868316 0.87 TERT (0.36) TERTALDH1A1DPP7METAP2METAP1
SCHEMBL25868310 0.87 TERT (0.36) TERTALDH1A1DPP7METAP2METAP1
SCHEMBL25868297 0.87 TERT (0.36) TERTALDH1A1DPP7METAP2METAP1
SCHEMBL26700213 0.86 FNTA (0.38) TERTALDH1A1DPP7RRM1
SCHEMBL26700211 0.86 FNTA (0.38) TERTALDH1A1DPP7RRM1
SCHEMBL25893116 0.85 DPP7 (0.36) TERTALDH1A1DPP7METAP2METAP1
SCHEMBL25893030 0.85 DPP7 (0.36) TERTALDH1A1DPP7METAP2METAP1
SCHEMBL25893029 0.85 DPP7 (0.36) TERTALDH1A1DPP7METAP2METAP1
SCHEMBL24256577 0.82 DPP7 (0.37) DPP7RRM1TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022035997-A1 IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS AVILAR THERAPEUTICS, INC. (US) 2022-02-17 WO disclosed