SCHEMBL24256797

SCHEMBL24256797

OCCCC1COC(CO)C(O)C1O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 3/20 0.40
TREH O43280 1/20 0.34
SPHK2 Q9NRA0 5/20 0.32
SPHK1 Q9NYA1 5/20 0.32
LGALS1 P09382 2/20 0.31
LGALS9 O00182 1/20 0.31
LGALS8 O00214 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25866991 1.00 LGALS3 (0.40) LGALS3TREHSPHK2SPHK1LGALS1
SCHEMBL23705239 1.00 LGALS3 (0.40) LGALS3TREHSPHK2SPHK1LGALS1
SCHEMBL24256557 0.81 LGALS3 (0.46) LGALS3TREHLGALS1LGALS9LGALS8
SCHEMBL23704952 0.81 LGALS3 (0.46) LGALS3TREHLGALS1LGALS9LGALS8
SCHEMBL30103366 0.81 LGALS3 (0.40) LGALS3TREHSPHK2SPHK1LGALS1
SCHEMBL24256594 0.81 LGALS3 (0.40) LGALS3TREHSPHK2SPHK1LGALS1
SCHEMBL23937263 0.81 LGALS3 (0.40) LGALS3TREHSPHK2SPHK1
SCHEMBL935701 0.80
SCHEMBL23705096 0.76 LGALS3 (0.42) LGALS3TREHLGALS1LGALS9LGALS8
SCHEMBL24916903 0.76 LGALS3 (0.42) LGALS3TREHSPHK2SPHK1LGALS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022035997-A1 IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS AVILAR THERAPEUTICS, INC. (US) 2022-02-17 WO disclosed