Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 3/20 | 0.40 |
| ▸ | TREH | O43280 | 1/20 | 0.34 |
| ▸ | IDUA | P35475 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.31 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24256594 | 1.00 | LGALS3 (0.40) | LGALS3TREHIDUASPHK2SPHK1 | |
| SCHEMBL25866971 | 0.84 | LGALS3 (0.42) | LGALS3TREHSILGALS1LGALS9 | |
| SCHEMBL26902707 | 0.84 | LGALS3 (0.42) | LGALS3TREHSILGALS1LGALS9 | |
| SCHEMBL23705096 | 0.84 | LGALS3 (0.42) | LGALS3TREHSILGALS1LGALS9 | |
| SCHEMBL24256557 | 0.81 | LGALS3 (0.46) | LGALS3TREHSILGALS1LGALS9 | |
| SCHEMBL23704952 | 0.81 | LGALS3 (0.46) | LGALS3TREHSILGALS1LGALS9 | |
| SCHEMBL24256797 | 0.81 | LGALS3 (0.40) | LGALS3TREHSPHK2SPHK1LGALS1 | |
| SCHEMBL23705239 | 0.81 | LGALS3 (0.40) | LGALS3TREHSPHK2SPHK1LGALS1 | |
| SCHEMBL23937263 | 0.81 | LGALS3 (0.40) | LGALS3TREHSPHK2SPHK1 | |
| SCHEMBL25866991 | 0.81 | LGALS3 (0.40) | LGALS3TREHSPHK2SPHK1LGALS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |