⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955437 | 0.75 | — | — | |
| SCHEMBL2023242 | 0.74 | APLNR (0.31) | — | |
| SCHEMBL3344251 | 0.72 | — | — | |
| SCHEMBL3650604 | 0.71 | — | — | |
| SCHEMBL19357451 | 0.71 | — | — | |
| SCHEMBL7921435 | 0.70 | — | — | |
| SCHEMBL924549 | 0.69 | — | — | |
| SCHEMBL9341323 | 0.69 | — | — | |
| SCHEMBL9341334 | 0.69 | — | — | |
| SCHEMBL16212911 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |