⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047080 | 0.81 | — | — | |
| SCHEMBL8562135 | 0.81 | — | — | |
| SCHEMBL8955437 | 0.76 | — | — | |
| SCHEMBL2023242 | 0.75 | APLNR (0.31) | — | |
| SCHEMBL7415796 | 0.75 | — | — | |
| SCHEMBL19357451 | 0.73 | — | — | |
| SCHEMBL7921435 | 0.71 | — | — | |
| SCHEMBL24256831 | 0.71 | — | — | |
| SCHEMBL4048189 | 0.70 | — | — | |
| SCHEMBL1314898 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185567-A2 | SUBSTITUTED BICYCLOLACTAM COMPOUNDS | Pfizer Products Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009016462-A2 | SUBSTITUTED BICYCLOLACTAM COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2009-02-05 | — | — | WO | disclosed |