SCHEMBL2425777

SCHEMBL2425777

CCN(O)C(=O)[C@@H](N)CC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.33
BHMT Q93088 1/20 0.33
GRIA4 P48058 1/20 0.33
GRIK3 Q13003 1/20 0.33
GRIK5 Q16478 1/20 0.33
DPP4 P27487 2/20 0.33
DPP9 Q86TI2 1/20 0.33
GRIK2 Q13002 1/20 0.32
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
GABRR1 P24046 2/20 0.32
LMNA P02545 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17503630 0.81 DPP4 (0.38) GRIK1BHMTGRIA4GRIK3GRIK5
SCHEMBL8436428 0.81 GABRR1 (0.33) GRIK1BHMTGRIA4GRIK3GRIK5
SCHEMBL15231379 0.80 SLC1A3 (0.35) DPP4DPP9SLC1A3SLC1A2SLC1A1
SCHEMBL16240225 0.76 BHMT (0.35) GRIK1BHMTGRIA4GRIK3GRIK5
SCHEMBL16240224 0.76 BHMT (0.35) GRIK1BHMTGRIA4GRIK3GRIK5
SCHEMBL24964979 0.76 DPP4 (0.39) GRIK1BHMTGRIA4GRIK3GRIK5
SCHEMBL10349046 0.76 DPP4 (0.39) GRIK1BHMTGRIA4GRIK3GRIK5
SCHEMBL31676717 0.75 SLC22A6 (0.39) GRIK1BHMTGRIA4GRIK3GRIK5
SCHEMBL7486136 0.75 GRIK1 (0.34) GRIK1DPP4GRIK2
SCHEMBL12593328 0.74 DPP4 (0.38) GRIK1BHMTGRIA4GRIK3GRIK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034930-B2 Biodegradable polymeric hydrogel composition COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-05-19 US disclosed
EP-2764351-A1 INTACT MASS DETERMINATION OF PROTEIN CONJUGATED AGENT COMPOUNDS Seattle Genetics, Inc. (US) 2014-08-13 EP disclosed
WO-2013049410-A1 INTACT MASS DETERMINATION OF PROTEIN CONJUGATED AGENT COMPOUNDS SEATTLE GENETICS, INC. (US) 2013-04-04 WO disclosed
US-20130059925-A1 Biodegradable Polymeric Hydrogel Composition COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-03-07 US disclosed
EP-2545100-A2 A BIODEGRADABLE POLYMERIC HYDROGEL COMPOSITION Council of Scientific & Industrial Research (IN) 2013-01-16 EP disclosed
WO-2011111067-A2 A BIODEGRADABLE POLYMERIC HYDROGEL COMPOSITION COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-09-15 WO disclosed