Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575774 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL14915522 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL22149208 | 0.93 | SMN1; SMN2 (0.44) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL14915520 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL14915840 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL1044605 | 0.82 | ALDH1A1 (0.45) | KDM4EPOLBLMNARAB9ANPC1 | |
| SCHEMBL2554045 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL5429818 | 0.81 | CDC7 (0.44) | AKR1C3AKR1C2KDM4ELMNAPRNP | |
| SCHEMBL2339344 | 0.79 | TSHR (0.49) | SMN1; SMN2KDM4ELMNATDP1ALDH1A1 | |
| SCHEMBL10665110 | 0.79 | ADRA1A (0.54) | KDM4ELMNATDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179087-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | Immunophage Biotech (Shanghai) Co., Ltd. (CN) | 2025-06-05 | — | — | US | disclosed |
| US-20220048887-A1 | IMPURITIES OF AMIDE-LIKE DERIVATIVES AND USE THEREOF | NHWA PHARMA. CORPORATION (CN) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048887-A1 | IMPURITIES OF AMIDE-LIKE DERIVATIVES AND USE THEREOF | NOTUM, CYP51A1, HADHB | SMN1; SMN2 3988/4885AKR1C3 1818/4885AKR1C2 781/4885 |
| US-20250179087-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | LPAR5, LPAR3, LPAR2 | SMN1; SMN2 3346/4885AKR1C3 606/4885AKR1C2 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.