SCHEMBL24257988

SCHEMBL24257988

O=C(O)CCCCCCCCCCCc1ccc(S(=O)(=O)Nc2ncc(C(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)O)cn2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CA2 P00918 7/20 0.39
HDAC6 Q9UBN7 1/20 0.38
PKM P14618 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.37
HDAC1 Q13547 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CA1 P00915 4/20 0.35
CA12 O43570 2/20 0.35
CA4 P22748 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22080333 1.00 NPC1 (0.40) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL22079946 1.00 NPC1 (0.40) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL31682070 1.00 NPC1 (0.40) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL22029401 1.00 NPC1 (0.40) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL22080331 0.96 TDP1 (0.38) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL24257961 0.95 SMN1; SMN2 (0.39) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL22080442 0.95 SMN1; SMN2 (0.39) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL24257857 0.94 TDP1 (0.44) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL22079977 0.94 TDP1 (0.44) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL31682051 0.94 TDP1 (0.44) NPC1RAB9AALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893934-B1 INSULIN CONJUGATES SANOFI SA (FR) 2025-09-10 EP disclosed
US-20220048968-A1 INSULIN CONJUGATES SANOFI (FR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048968-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R NPC1 3240/4885RAB9A 2867/4885ALDH1A1 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.