Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258341 | 0.79 | PTPN2 (0.38) | LSSMAOB | |
| SCHEMBL24258401 | 0.73 | DAO (0.32) | DAOKDM1AMAOAMAOB | |
| SCHEMBL14318720 | 0.72 | NPC1 (0.40) | — | |
| SCHEMBL9083096 | 0.71 | NPC1 (0.39) | — | |
| SCHEMBL9084823 | 0.69 | CEL (0.34) | — | |
| SCHEMBL9084589 | 0.68 | LPL (0.34) | — | |
| SCHEMBL9083040 | 0.68 | HTR2A (0.34) | — | |
| SCHEMBL17141772 | 0.67 | ESR2 (0.39) | — | |
| SCHEMBL1310810 | 0.67 | DAO (0.47) | DAOKDM1AMAOAMAOB | |
| SCHEMBL9082717 | 0.67 | CEL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177612-B1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION AS (DK) | 2022-02-23 | — | — | EP | disclosed |