Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | FHIT | P49789 | 5/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.38 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258668 | 0.93 | TAS1R3 (0.42) | BCHETAS1R3TAS1R1FHITP2RX3 | |
| SCHEMBL24258656 | 0.93 | TAS1R3 (0.42) | BCHETAS1R3TAS1R1FHITP2RX3 | |
| SCHEMBL24258669 | 0.85 | TAS1R3 (0.42) | BCHETAS1R3TAS1R1FHITP2RX3 | |
| SCHEMBL24444145 | 0.83 | POLB (0.46) | TAS1R3TAS1R1FHITP2RX3P2RX2 | |
| SCHEMBL24258606 | 0.81 | POLB (0.42) | BCHETAS1R3TAS1R1FHITP2RX3 | |
| SCHEMBL22571145 | 0.80 | BCHE (0.53) | BCHETAS1R3TAS1R1FHITP2RX3 | |
| SCHEMBL24258562 | 0.79 | BCHE (0.42) | BCHEFHIT | |
| SCHEMBL22524142 | 0.77 | BCHE (0.55) | BCHETAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL24258560 | 0.76 | NT5E (0.43) | TAS1R3TAS1R1FHITP2RX3P2RX2 | |
| SCHEMBL24258563 | 0.75 | FHIT (0.39) | BCHETAS1R3TAS1R1FHITP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752516-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-02-23 | — | — | EP | disclosed |