SCHEMBL2425984

SCHEMBL2425984

Fc1ccncc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30271437 1.00
SCHEMBL29530920 0.81
SCHEMBL317186 0.81
Hydrochloric Acid SCHEMBL6587121 0.79
Formaldehyde SCHEMBL27955098 0.75 LOXL2 (0.43)
SCHEMBL31145055 0.75
SCHEMBL29518741 0.75
SCHEMBL952595 0.75
SCHEMBL3717170 0.75
SCHEMBL31301252 0.72 GSK3B (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110914255-B Organic molecules, in particular for optoelectronic devices 三星显示有限公司 2023-03-31 CN disclosed
EP-3797102-B1 CARBAZOLE-PYRIDINE-CYANOPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS LUMINESCENT EMITTERS IN OLEDS SAMSUNG DISPLAY CO LTD (KR) 2022-11-16 EP disclosed
EP-3724179-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2022-02-09 EP disclosed
EP-3724179-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2022-02-09 EP disclosed
EP-3797102-A1 CARBAZOLE-PYRIDINE-CYANOPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS LUMINESCENT EMITTERS IN OLEDS cynora GmbH (DE) 2021-03-31 EP disclosed
EP-3575377-B1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-03-17 EP disclosed
US-10919858-B2 Thioacetate compounds, compositions and methods of use ARDEA BIOSCIENCES, INC (US) 2021-02-16 US disclosed
EP-3724179-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES cynora GmbH (DE) 2020-10-21 EP disclosed
EP-3223820-B1 3-METHYL-2-IMINO-HEXAHYDRO-1H-PYRANO[3,4-D]PYRIMIDIN-4-ONE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE MERCK SHARP & DOHME (US) 2020-07-22 EP disclosed
CN-110914255-A Organic molecules, in particular for optoelectronic devices 辛诺拉有限公司 2020-03-24 CN disclosed
US-20190185431-A1 THIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE ARDEA BIOSCIENCES, INC. 2019-06-20 US disclosed
WO-2019115446-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-06-20 WO disclosed
WO-2019115446-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-06-20 WO disclosed
WO-2018112094-A1 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE AMGEN INC. (US) 2018-06-21 WO disclosed
US-20170362248-A1 C5-C6-OXACYCLIC FUSED IMINOPYRIMIDINONE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE MERCK SHARP & DOHME CORP. (US) 2017-12-21 US disclosed
US-20170362248-A1 C5-C6-OXACYCLIC FUSED IMINOPYRIMIDINONE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE MERCK SHARP & DOHME CORP. (US) 2017-12-21 US disclosed
EP-2366699-B1 8-SUBSTITUTED ISOQUINOLINE DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2013-08-07 EP disclosed
US-8299055-B2 8-substituted isoquinoline derivative and the use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2012-10-30 US disclosed
EP-2366699-A1 8-SUBSTITUTED ISOQUINOLINE DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2011-09-21 EP disclosed
US-20100261701-A1 8-Substituted isoquinoline derivative and the use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2010-10-14 US disclosed