Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18908828 | 0.79 | HSD17B10 (0.36) | HSD17B10CYP1A2MAPTNPC1RAB9A | |
| SCHEMBL18908830 | 0.79 | SMN1; SMN2 (0.36) | HSD17B10CYP1A2MAPTNPC1RAB9A | |
| SCHEMBL19454394 | 0.79 | NPC1 (0.42) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23730779 | 0.79 | HTR2C (0.37) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18908798 | 0.72 | ALDH1A1 (0.36) | HSD17B10CYP1A2MAPTNPC1RAB9A | |
| SCHEMBL18908812 | 0.72 | ALDH1A1 (0.36) | HSD17B10CYP1A2MAPTNPC1RAB9A | |
| SCHEMBL19491224 | 0.71 | IL1B (0.36) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18908797 | 0.70 | IL1B (0.33) | SMN1; SMN2 | |
| SCHEMBL30189427 | 0.70 | CYP2A6 (0.43) | HSD17B10CYP1A2MAPTALDH1A1KDM4E | |
| SCHEMBL19404374 | 0.70 | HSD17B10 (0.39) | HSD17B10CYP1A2MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444245-B1 | HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2022-02-23 | — | — | EP | disclosed |