Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | RARA | P10276 | 5/20 | 0.50 |
| ▸ | RARG | P13631 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755595 | 0.81 | MEN1 (0.55) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL549446 | 0.80 | MEN1 (0.73) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL396121 | 0.79 | MEN1 (0.51) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL22321006 | 0.79 | MEN1 (0.51) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL178123 | 0.79 | MEN1 (0.51) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL25635949 | 0.79 | MEN1 (0.51) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL566145 | 0.79 | MEN1 (0.51) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL548836 | 0.78 | MEN1 (0.53) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL6368048 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL548700 | 0.77 | MEN1 (0.52) | ALDH1A1MEN1KMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044216-B1 | NOVEL AND SPECIFIC INHIBITORS OF CYTOCHROME P450 26 RETINOIC ACID HYDROXYLASE | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2022-02-23 | — | — | EP | disclosed |