SCHEMBL178123

SCHEMBL178123

Oc1ccc(Br)cc1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
GFER P55789 1/20 0.51
RARB P10826 5/20 0.50
RARA P10276 5/20 0.50
RARG P13631 4/20 0.50
ALOX15 P16050 2/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14627878 0.92 RARB (0.44) MEN1KMT2APOLBGAAGFER
SCHEMBL403671 0.87 HDAC11 (0.61) MEN1KMT2APOLBGAAGFER
SCHEMBL30179323 0.87 HDAC11 (0.61) MEN1KMT2APOLBGAAGFER
SCHEMBL1913921 0.86 RARB (0.44) MEN1KMT2APOLBGAAGFER
SCHEMBL6033366 0.86 MEN1 (0.47) MEN1KMT2APOLBGAAGFER
SCHEMBL7687459 0.82 MEN1 (0.59) MEN1KMT2APOLBGAAGFER
SCHEMBL3755595 0.81 MEN1 (0.55) MEN1KMT2APOLBGAAGFER
SCHEMBL549446 0.80 MEN1 (0.73) MEN1KMT2APOLBGAAGFER
SCHEMBL25558997 0.79 MEN1 (0.43) MEN1KMT2APOLBGAAGFER
SCHEMBL24259966 0.79 ALDH1A1 (0.52) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010697-A Preparation method of adapalene key intermediate 江苏联环药业股份有限公司 2026-05-12 CN claimed
CN-117736071-A Method for continuously preparing 2- ((3 r,5r,7 r) -adamantan-1-yl) -4-bromophenol 南京恒道医药科技股份有限公司 2024-03-22 CN claimed
CN-101955417-B Method for preparing 2-(1-adamantyl)-4-bromophenol UNIV EAST CHINA SCIENCE & TECH 2013-01-02 CN claimed
CN-101955417-A Method for preparing 2-(1-adamantyl)-4-bromophenol UNIV EAST CHINA SCIENCE & TECH 2011-01-26 CN claimed
CN-1827582-A Process for preparing 6-[3-(1-adamantyl)-4-methoxy phenyl]-2-methyl naphthoate JIANGSU ZHONGDAN CHEMICAL GROU (CN) 2006-09-06 CN claimed
CN-122010697-A Preparation method of adapalene key intermediate 江苏联环药业股份有限公司 2026-05-12 CN disclosed
US-20260035353-A1 PHENOL DERIVATIVES FOR USE AS ANTIMICROBIAL, ANTIBACTERIAL, BACTERICIDE SPECIAL PRODUCTS LINE S P A (IT) 2026-02-05 US disclosed
US-20250277065-A1 Substituted Pyridine-2,6-bis(phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-09-04 US disclosed
CN-119684107-A Method for purifying adapalene bulk drug 河北华晨药业集团有限公司 2025-03-25 CN disclosed
EP-4519331-A1 SUBSTITUTED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2025-03-12 EP disclosed
EP-3519383-B1 RETINOID DERIVATIVES WITH ANTITUMOR ACTIVITY BIOGEM S C A R L (IT) 2024-08-21 EP disclosed
CN-117736071-A Method for continuously preparing 2- ((3 r,5r,7 r) -adamantan-1-yl) -4-bromophenol 南京恒道医药科技股份有限公司 2024-03-22 CN disclosed
US-4940696-A Benzonaphthalene derivatives and their use in therapeutic and cosmetic compositions CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIOUES (CIRD) (FR) 1990-07-10 US disclosed
US-4927928-A SKIN DISORDERS, EYES, ANTITUMOR CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) 1990-05-22 US disclosed
US-4920140-A Skin disorders CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) 1990-04-24 US disclosed
EP-0199636-B1 BENZONAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PHARMACY AND COSMETICS CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. Groupement d'Intérêt Economique dit: (FR) 1989-02-08 EP disclosed
US-4740519-A Benzo (b) thiophene carboxylate derivatives and pharmaceutical compositions CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) 1988-04-26 US disclosed
US-4717720-A DERMATOLOGIC DISEASES, CONJUCTIVE TISSUE DEGENERATION AND ANTI-TUMOR ACTIVITY CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) 1988-01-05 US disclosed
EP-0232199-A2 Aromatic benzamido compounds, process for their preparation and their use in human or veterinary medicine as well as in cosmetics CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) 1987-08-12 EP disclosed
EP-0199636-A1 Benzonaphthalenic derivatives, process for their preparation and their use in pharmacy and cosmetics CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. Groupement d'Intérêt Economique dit: (FR) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035353-A1 PHENOL DERIVATIVES FOR USE AS ANTIMICROBIAL, ANTIBACTERIAL, BACTERICIDE TLR7, GANC, ARG1 MEN1 4747/4885KMT2A 4794/4885POLB 1748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.