Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4048447 | 1.00 | — | — | |
| Bromide SCHEMBL8165594 | 0.95 | ALDH1A1 (0.39) | — | |
| SCHEMBL18185998 | 0.94 | ALDH1A1 (0.46) | — | |
| SCHEMBL285 | 0.94 | — | — | |
| Fluoride SCHEMBL9698194 | 0.94 | — | — | |
| SCHEMBL5084531 | 0.94 | — | — | |
| SCHEMBL145743 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL23466884 | 0.89 | ALDH1A1 (0.42) | — | |
| SCHEMBL5820312 | 0.89 | ALDH1A1 (0.42) | — | |
| SCHEMBL11125555 | 0.89 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141933-A2 | PROCESS FOR PREPARATION OF 2-[3-CYANO-4-(2-METHYLPROPOXY)PHENYL]-4-METHYLTHIAZOLE-5-CARBOXYLIC ACID AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | MSN LABORATORIES LIMITED (IN) | 2011-11-17 | — | — | WO | claimed |
| JP-4711950-B2 | — | — | 2011-06-29 | — | — | JP | claimed |
| EP-1633750-B1 | SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAINDOLINES | EISAI R&D MAN CO LTD (JP) | 2010-12-01 | — | — | EP | claimed |
| US-7652137-B2 | Substitued azaindoline intermediate for use in the manufacture of 5-substituted 7-azaindolines and 5-substituted 7-azaindoles; pharmaceutical intermediates | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2010-01-26 | — | — | US | claimed |
| US-7271302-B1 | Method for brominating organic compounds | MERCK PATENT GESELLSCHAFT (DE) | 2007-09-18 | — | — | US | claimed |
| US-20060235042-A1 | Synthesis | EISAI CO., LTD. (JP) | 2006-10-19 | — | — | US | claimed |
| JP-2006520771-A | — | — | 2006-09-14 | — | — | JP | claimed |
| EP-1633750-A2 | SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAINDOLINES | Eisai Co., Ltd. (JP) | 2006-03-15 | — | — | EP | claimed |
| WO-2004078757-A2 | SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAIDONINES | EISAI CO., LTD. (JP) | 2004-09-16 | — | — | WO | claimed |
| EP-0054795-B1 | NOVEL HALOGENATED PROSTACYCLINS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1987-07-15 | — | — | EP | claimed |
| EP-0054795-A2 | Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1982-06-30 | — | — | EP | claimed |
| JP-55079336-A | — | — | None | — | — | JP | disclosed |
| EP-3778667-B1 | 4-METHYL-1-PENTENE POLYMER PARTICLES AND METHOD OF PRODUCING 4-METHYL-1-PENTENE RESIN | MITSUI CHEMICALS INC (JP) | 2025-09-03 | — | — | EP | disclosed |
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | disclosed |
| US-11485815-B2 | 4-methyl-1-pentene polymer particle and method for producing 4-methyl-1-pentene resin | MITSUI CHEMICALS, INC. (JP) | 2022-11-01 | — | — | US | disclosed |
| US-4118507-A | Benzodioxincarboxamide lipogenesis inhibitors | SHELL OIL COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4112000-A | BACTERIOSTATS | MAR-PHA, SOCIETE D'ETUDE ET D'EXPLOITATION DE MARQUES (FR) | 1978-09-05 | — | — | US | disclosed |
| US-4103021-A | BENZODIOXIN AND BENZOPYRAN CARBOXAMIDES | SHELL OIL COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4036864-A | Chemical process | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1977-07-19 | — | — | US | disclosed |
| US-3935009-A | FLUOREN-9-YLIDENE | OCE-VAN DER GRINTEN N.V. (NL) | 1976-01-27 | — | — | US | disclosed |