Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2426 | 1.00 | — | — | |
| Bromide SCHEMBL8165594 | 0.95 | ALDH1A1 (0.39) | — | |
| SCHEMBL18185998 | 0.94 | ALDH1A1 (0.46) | — | |
| SCHEMBL285 | 0.94 | — | — | |
| Fluoride SCHEMBL9698194 | 0.94 | — | — | |
| SCHEMBL5084531 | 0.94 | — | — | |
| SCHEMBL145743 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL23466884 | 0.89 | ALDH1A1 (0.42) | — | |
| SCHEMBL5820312 | 0.89 | ALDH1A1 (0.42) | — | |
| SCHEMBL11125555 | 0.89 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107267191-A | With the method for nitride in imidazole type dication liquid removal diesel oil | 宁波大学 | 2017-10-20 | — | — | CN | claimed |
| CN-1302008-C | Synthetic method for N(2)-L-alanyl-L-glutamine dipeptide | UNIV XIAMEN (CN) | 2007-02-28 | — | — | CN | claimed |
| CN-1683391-A | Synthetic method for N(2)-L-alanyl-L-glutamine dipeptide | UNIV XIAMEN (CN) | 2005-10-19 | — | — | CN | claimed |
| CN-114456223-B | Synthesis method of 3-ketal | 湖南科益新生物医药有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114456223-A | Method for synthesizing 3-ketal | 湖南科益新生物医药有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-108854841-A | A kind of pyrrolidines chirality Gemini surface active and preparation method thereof of the linker containing ester group | 长治学院 | 2018-11-23 | — | — | CN | disclosed |
| CN-104744666-B | Segment type polymeric material of conjugated chain containing more piece and its preparation method and application | 中国科学院上海有机化学研究所 | 2017-11-07 | — | — | CN | disclosed |
| CN-107266681-A | Amine polymer as bile acid sequestrant | 瑞立普萨公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-107267191-A | With the method for nitride in imidazole type dication liquid removal diesel oil | 宁波大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-107267191-A | With the method for nitride in imidazole type dication liquid removal diesel oil | 宁波大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-102906159-B | Amine polymers as bile acid sequestrants | 瑞立普萨公司 | 2017-09-26 | — | — | CN | disclosed |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2004-04-01 | — | — | US | disclosed |
| EP-1373244-A2 | SUBSTITUTED BENZOPYRANONES AS TELOMERASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-02 | — | — | EP | disclosed |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2002-10-31 | — | — | US | disclosed |
| WO-2002074036-A2 | SUBSTITUTED BENZOPYRANONES AS TELOMERASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2002-09-26 | — | — | WO | disclosed |
| US-4576753-A | MICROBIOCIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| US-4472309-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4304718-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |
| US-4032598-A | TREATMENT WITH A BASE | MARUZEN OIL CO. LTD. (JA) | 1977-06-28 | — | — | US | disclosed |