Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.66 |
| ▸ | AOC2 | O75106 | 2/20 | 0.49 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437012 | 0.91 | GPR119 (0.80) | GPR119AOC2 | |
| SCHEMBL1575162 | 0.89 | GPR119 (0.84) | GPR119 | |
| SCHEMBL1576025 | 0.82 | GPR119 (0.79) | GPR119 | |
| SCHEMBL14905519 | 0.82 | GPR119 (0.56) | GPR119MOGAT2 | |
| SCHEMBL1575600 | 0.82 | GPR119 (0.82) | GPR119 | |
| SCHEMBL4599249 | 0.81 | GPR119 (0.55) | GPR119 | |
| SCHEMBL12325541 | 0.81 | GPR119 (0.53) | GPR119 | |
| SCHEMBL2431556 | 0.81 | GPR119 (0.63) | GPR119 | |
| SCHEMBL14621363 | 0.81 | GPR119 (0.60) | GPR119AOC2 | |
| SCHEMBL1575669 | 0.81 | GPR119 (0.79) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377863-A1 | Piperidine GPCR agonists | Prosidion Limited (GB) | 2011-10-19 | — | — | EP | disclosed |
| EP-2114933-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2011-09-07 | — | — | EP | disclosed |
| US-20100048632-A1 | Piperidine GPCR Agonists | PROSIDION LIMITED (GB) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048632-A1 | Piperidine GPCR Agonists | GPR119, GPR27, GLP1R | GPR119 1/4885AOC2 2826/4885MOGAT2 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.