SCHEMBL24263262 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	TYK2	P29597	17/20	0.40

▸	STAT3	P40763	3/20	0.40

▸	HPGDS	O60760	1/20	0.40

▸	F10	P00742	2/20	0.38

▸	JAK2	O60674	1/20	0.36

▸	KIT	P10721	1/20	0.36

▸	JAK1	P23458	1/20	0.36

▸	KCNH2	Q12809	1/20	0.36

▸	PDE4D	Q08499	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24263490	0.86	TYK2 (0.43)	TYK2STAT3HPGDSPDE4D
SCHEMBL24263278	0.86	TYK2 (0.56)	TYK2STAT3
SCHEMBL24263411	0.84	TYK2 (0.57)	TYK2STAT3
SCHEMBL24263263	0.83	HPGDS (0.46)	TYK2STAT3HPGDSF10
SCHEMBL24263260	0.83	HPGDS (0.46)	TYK2STAT3HPGDSF10
SCHEMBL24263496	0.83	HPGDS (0.46)	TYK2STAT3HPGDSF10
SCHEMBL24263494	0.83	TYK2 (0.56)	TYK2STAT3
SCHEMBL24263415	0.83	TYK2 (0.40)	TYK2STAT3HPGDSPDE4D
SCHEMBL24263562	0.81	HPGDS (0.42)	TYK2STAT3HPGDSF10
SCHEMBL24263261	0.81	TYK2 (0.57)	TYK2STAT3PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022037694-A1	A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS	轶诺(浙江)药业有限公司	2022-02-24	—	—	WO	disclosed