Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 15/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263490 | 0.92 | TYK2 (0.43) | TYK2STAT3PDE4DHPGDSCNR2 | |
| SCHEMBL24263399 | 0.86 | TYK2 (0.47) | TYK2STAT3 | |
| SCHEMBL24263418 | 0.84 | TYK2 (0.52) | TYK2STAT3PDE4D | |
| SCHEMBL24263413 | 0.83 | TYK2 (0.41) | TYK2PDE4D | |
| SCHEMBL24263262 | 0.83 | TYK2 (0.40) | TYK2STAT3PDE4DHPGDS | |
| SCHEMBL24263383 | 0.82 | TYK2 (0.47) | TYK2STAT3HPGDS | |
| SCHEMBL24263289 | 0.82 | TYK2 (0.54) | TYK2STAT3 | |
| SCHEMBL24263263 | 0.80 | HPGDS (0.46) | TYK2STAT3HPGDSCNR2 | |
| SCHEMBL24263496 | 0.80 | HPGDS (0.46) | TYK2STAT3HPGDSCNR2 | |
| SCHEMBL24263260 | 0.80 | HPGDS (0.46) | TYK2STAT3HPGDSCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |