Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263509 | 0.91 | GPR6 (0.35) | SMN1; SMN2GPR6TYK2PDE4D | |
| SCHEMBL20504574 | 0.88 | IDO1 (0.37) | GAAKMT2AMEN1IDO1NPSR1 | |
| SCHEMBL24263379 | 0.87 | TYK2 (0.46) | GAAIDO1NPSR1ADORA3ADORA2A | |
| SCHEMBL16794637 | 0.86 | TYK2 (0.45) | GAAKMT2AMEN1IDO1NPSR1 | |
| SCHEMBL16794711 | 0.85 | TYK2 (0.39) | GAAKMT2AMEN1IDO1NPSR1 | |
| SCHEMBL20557551 | 0.85 | TYK2 (0.45) | GAAKMT2AMEN1IDO1NPSR1 | |
| SCHEMBL20557221 | 0.83 | MAPT (0.39) | GAAKMT2AMEN1IDO1NPSR1 | |
| SCHEMBL31245746 | 0.83 | TYK2 (0.41) | TYK2 | |
| SCHEMBL16794693 | 0.82 | MAPT (0.42) | GAAKMT2AMEN1IDO1P2RY12 | |
| SCHEMBL24263282 | 0.80 | TYK2 (0.52) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |