Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 5/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ASPH | Q12797 | 2/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.33 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.33 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.33 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263290 | 0.91 | GAA (0.37) | GPR6TYK2PDE4DSMN1; SMN2 | |
| SCHEMBL20504588 | 0.88 | TYK2 (0.39) | TYK2PDE4DSMN1; SMN2CLK1ZAP70 | |
| SCHEMBL24263403 | 0.86 | TYK2 (0.48) | TYK2PDE4DSMN1; SMN2KDM4EZAP70 | |
| SCHEMBL16794686 | 0.85 | TYK2 (0.47) | TYK2PDE4D | |
| SCHEMBL16794699 | 0.83 | TYK2 (0.41) | TYK2PDE4DSMN1; SMN2PTPN1KDM4E | |
| SCHEMBL24263413 | 0.83 | TYK2 (0.41) | TYK2PDE4DPTPN1TAS2R14 | |
| SCHEMBL20049469 | 0.83 | TYK2 (0.46) | TYK2PDE4DSMN1; SMN2 | |
| SCHEMBL31245711 | 0.82 | TYK2 (0.43) | TYK2PDE4D | |
| SCHEMBL16794676 | 0.81 | PDE1B (0.40) | SMN1; SMN2PTPN1NR3C1PDE1BTAS2R14 | |
| SCHEMBL24263286 | 0.79 | TYK2 (0.55) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |