Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324181 | 0.79 | HTT (0.74) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15656249 | 0.77 | ALDH1A1 (0.77) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15654670 | 0.73 | HTT (0.65) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL16566259 | 0.73 | ALDH1A1 (0.55) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5283603 | 0.72 | HTT (0.60) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL26508519 | 0.70 | HTT (0.61) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL26508546 | 0.70 | HTT (0.60) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5298727 | 0.68 | ALDH1A1 (0.57) | HTTALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL8684343 | 0.68 | HTT (0.57) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5323778 | 0.68 | ALDH1A1 (0.57) | HTTALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037648-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | 北京大学 | 2022-02-24 | — | — | WO | disclosed |