Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282599 | 0.78 | HTT (0.64) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5324181 | 0.76 | HTT (0.74) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9299345 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4ESMN1; SMN2POLB | |
| SCHEMBL15656249 | 0.74 | ALDH1A1 (0.77) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL22234295 | 0.72 | ESR1 (0.57) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1126957 | 0.72 | ALDH1A1 (0.50) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL13307806 | 0.71 | MEN1 (0.68) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5966757 | 0.71 | HTT (0.52) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15654670 | 0.71 | HTT (0.65) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2049182 | 0.70 | ALDH1A1 (0.65) | HTTALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723481-A | ANTIULCER AGENTS AND 5-LIPOXYGENASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5698576-A | POSSESS ANTI-ULCER AND 5-LIPOXYGENASE INHIBITORY ACTIVITIES | SANKYO COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5665752-A | LIPOXYGENASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1997-09-09 | — | — | US | disclosed |
| US-5354768-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0353047-B1 | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO CO (JP) | 1994-10-05 | — | — | EP | disclosed |
| US-5232939-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0353047-A2 | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | Sankyo Company Limited (JP) | 1990-01-31 | — | — | EP | disclosed |