Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.97 |
| ▸ | PGR | P06401 | 1/20 | 0.97 |
| ▸ | GAA | P10253 | 1/20 | 0.97 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.97 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | OGG1 | O15527 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbaril SCHEMBL29370871 | 0.98 | ALDH1A1 (1.00) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL374307 | 0.98 | ALDH1A1 (1.00) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL26737 | 0.98 | ALDH1A1 (1.00) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL9515092 | 0.97 | ALDH1A1 (0.97) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL3474939 | 0.97 | ALDH1A1 (0.97) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL8855245 | 0.97 | ALDH1A1 (0.97) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL2521354 | 0.97 | ALDH1A1 (0.97) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL6054746 | 0.97 | ALDH1A1 (0.97) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL5197395 | 0.97 | ALDH1A1 (0.97) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Carbaril SCHEMBL15572922 | 0.95 | ALDH1A1 (0.93) | ALDH1A1HSD17B10PGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017524-B2 | Stable, high rate silicon slurry | CABOT MICROELECTRONICS CORPORATION (US) | 2011-09-13 | — | — | US | claimed |
| US-20230002371-A1 | RAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX INC (US) | 2023-01-05 | — | — | US | disclosed |
| WO-2021051034-A1 | RAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| US-10329272-B2 | Microbiocidal heterobicyclic derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-25 | — | — | US | disclosed |
| EP-3334715-B1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-22 | — | — | EP | disclosed |
| EP-3334715-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | Syngenta Participations AG (CH) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017025509-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-16 | — | — | WO | disclosed |
| US-4894480-A | Phenyl substituted-2,4,6,8-nonatetraenoic acid | HOFFMANN-LA ROCHE INC. (US) | 1990-01-16 | — | — | US | disclosed |
| US-4883613-A | TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1989-11-28 | — | — | US | disclosed |
| US-4883614-A | TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1989-11-28 | — | — | US | disclosed |
| US-4780251-A | ANTIRHEUMATIC AGENTS, IMMUNOSUPPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0252404-A2 | 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1988-01-13 | — | — | EP | disclosed |
| US-4648996-A | ANTIRHEUMATIC AGENTS, IMMUNOSUPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1987-03-10 | — | — | US | disclosed |
| US-4543256-A | (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers | NORTHEASTERN UNIVERSITY (US) | 1985-09-24 | — | — | US | disclosed |
| US-4429166-A | Method of preparing bicyclo(3.1.1)hept-2-one | RESEARCH CORPORATION (US) | 1984-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329272-B2 | Microbiocidal heterobicyclic derivatives | MSR1, C1R, C3AR1 | ALDH1A1 2864/4885HSD17B10 3487/4885PGR 3476/4885 |
| US-20230002371-A1 | RAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | KRAS, RSU1, RAB1A | ALDH1A1 2964/4885HSD17B10 3834/4885PGR 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.