Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19641648 | 0.88 | PGR (0.43) | SLC6A2SLC6A3SLC6A4PGRAR | |
| SCHEMBL28567534 | 0.85 | PGR (0.48) | SLC6A2SLC6A3SLC6A4PGRAR | |
| SCHEMBL21083953 | 0.84 | HRH3 (0.43) | PGRARFFAR4ACACBHRH3 | |
| SCHEMBL24266829 | 0.83 | PGR (0.54) | SLC6A2SLC6A3SLC6A4PGRAR | |
| SCHEMBL19643696 | 0.82 | SLC6A2 (0.37) | SLC6A2SLC6A3SLC6A4PGRAR | |
| SCHEMBL19643694 | 0.82 | SLC6A2 (0.37) | SLC6A2SLC6A3SLC6A4PGRAR | |
| SCHEMBL19641872 | 0.81 | PGR (0.38) | SLC6A2SLC6A3SLC6A4PGRAR | |
| SCHEMBL19643008 | 0.81 | PGR (0.38) | SLC6A2SLC6A3SLC6A4PGRAR | |
| SCHEMBL24266827 | 0.80 | AR (0.60) | AR | |
| SCHEMBL22557802 | 0.78 | PGR (0.43) | SLC6A2SLC6A3SLC6A4PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |