Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19641648 | 0.93 | PGR (0.43) | PGRMPOHRH3ARSLC6A2 | |
| SCHEMBL22557803 | 0.92 | PGR (0.43) | PGRMPOHRH3ARSLC6A2 | |
| SCHEMBL22557802 | 0.92 | PGR (0.43) | PGRMPOHRH3ARSLC6A2 | |
| SCHEMBL22565508 | 0.92 | PGR (0.46) | PGRMPOHRH3ARACACB | |
| SCHEMBL21083953 | 0.92 | HRH3 (0.43) | PGRMPOHRH3ARFFAR4 | |
| SCHEMBL24298595 | 0.87 | ACSL1 (0.46) | PGRARFFAR4ACACBNPC1 | |
| SCHEMBL24299375 | 0.87 | ACSL1 (0.46) | PGRARFFAR4ACACBNPC1 | |
| SCHEMBL15634155 | 0.86 | PGR (0.45) | PGRMPOHRH3ARSLC6A2 | |
| SCHEMBL22717471 | 0.85 | ALK (0.37) | PGRMPOHRH3ARSLC6A2 | |
| SCHEMBL24266830 | 0.85 | SLC6A2 (0.38) | PGRMPOHRH3ARSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265352-B | Preparation method of aryl cyclopropyl ether and derivatives thereof | 杭州迈世腾药物科技有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-109265352-B | Preparation method of aryl cyclopropyl ether and derivatives thereof | 杭州迈世腾药物科技有限公司 | 2021-06-04 | — | — | CN | disclosed |