Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 3/20 | 0.30 |
| ▸ | SI | P14410 | 3/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24117185 | 0.81 | ALDH1A1 (0.34) | CDK4CCND1ALDH1A1TSHRMAPK1 | |
| SCHEMBL24266559 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1ATMHSD17B10 | |
| SCHEMBL21630342 | 0.76 | ALDH1A1 (0.54) | CDK4CCND1ALDH1A1TSHRMAPK1 | |
| SCHEMBL24266885 | 0.76 | CDK4 (0.46) | CDK4CCND1ALDH1A1TSHRMAPK1 | |
| SCHEMBL23024713 | 0.74 | CDK4 (0.46) | CDK4CCND1ALDH1A1TSHRMAPK1 | |
| SCHEMBL19257496 | 0.72 | CDK4 (0.38) | CDK4CCND1 | |
| SCHEMBL10014625 | 0.70 | IMPDH2 (0.45) | CDK4CCND1ALDH1A1ATMHSD17B10 | |
| SCHEMBL23771655 | 0.70 | CDK4 (0.46) | CDK4CCND1MAPK1ATM | |
| SCHEMBL19257380 | 0.69 | CDK4 (0.35) | CDK4CCND1ALDH1A1TSHRMAPK1 | |
| SCHEMBL19257407 | 0.69 | CDK4 (0.36) | CDK4CCND1ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220059777-A1 | PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2022-02-24 | — | — | US | disclosed |