Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291745 | 0.88 | EPHX2 (0.64) | NAMPTL3MBTL1HDAC1EPHX2NR1H4 | |
| SCHEMBL3180689 | 0.87 | L3MBTL1 (0.61) | NAMPTL3MBTL1HDAC1HDAC6HDAC10 | |
| SCHEMBL6622954 | 0.87 | NAMPT (0.59) | NAMPTL3MBTL1HDAC1EPHX2NR1H4 | |
| SCHEMBL8220824 | 0.86 | EPHX2 (0.60) | NAMPTL3MBTL1HDAC1EPHX2NR1H4 | |
| SCHEMBL8338878 | 0.86 | NAMPT (0.56) | NAMPTL3MBTL1HDAC1EPHX2NR1H4 | |
| SCHEMBL23899245 | 0.85 | NAMPT (0.72) | NAMPTL3MBTL1HDAC1EPHX2NR1H4 | |
| SCHEMBL2511243 | 0.85 | CA2 (0.55) | NAMPTCA1CA2NPC1RAB9A | |
| SCHEMBL5736115 | 0.85 | HDAC1 (0.60) | NAMPTL3MBTL1HDAC1EPHX2NR1H4 | |
| SCHEMBL23775465 | 0.85 | ALDH1A1 (0.58) | NAMPTL3MBTL1HDAC1EPHX2NR1H4 | |
| SCHEMBL18295371 | 0.85 | L3MBTL1 (0.54) | NAMPTL3MBTL1HDAC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163049-A1 | FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS USP1 INHIBITORS | EXELIXIS INC (US) | 2025-05-22 | — | — | US | disclosed |
| EP-4472946-A1 | FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS USP1 INHIBITORS | Exelixis, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| US-12103928-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2024-10-01 | — | — | US | disclosed |
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-11731971-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-08-22 | — | — | US | disclosed |
| WO-2023148643-A1 | FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS USP1 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-08-10 | — | — | WO | disclosed |
| EP-3328843-B1 | 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2022-10-26 | — | — | EP | disclosed |
| US-20210371419-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-11117896-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| CN-108137518-B | 1,3, 4-oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same | 株式会社钟根堂 | 2021-08-31 | — | — | CN | disclosed |
| WO-2011123678-A2 | SUBSTITUTED BENZO-PYRIDO-TRIAZOLO-DIAZEPINE COMPOUNDS | ARQULE, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011123678-A2 | SUBSTITUTED BENZO-PYRIDO-TRIAZOLO-DIAZEPINE COMPOUNDS | ARQULE, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110245236-A1 | Substituted Benzo-Pyrido-Triazolo-Diazepine Compounds | ARQULE, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-20110245236-A1 | Substituted Benzo-Pyrido-Triazolo-Diazepine Compounds | ARQULE, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-5981531-A | FOR INHIBITING PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |
| US-5760057-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1998-06-02 | — | — | US | disclosed |
| EP-0632016-B1 | 1,2-Diacylated hydrazine derivatives and their use as cell adhesion inhibitors | ZENECA LTD (GB) | 1997-04-09 | — | — | EP | disclosed |
| US-5612373-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1997-03-18 | — | — | US | disclosed |
| WO-1995000472-A1 | 1,2 DIACYLATED HYDRAZINE DERIVATIVES AND THEIR USE AS ALL ADHESION INHIBITORS | ZENECA LIMITED (GB) | 1995-01-05 | — | — | WO | disclosed |
| EP-0632016-A1 | 1,2-Diacylated hydrazine derivatives and their use as cell adhesion inhibitors | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731971-B2 | Processes for preparing a diazabicyclooctane compound | FN1, BMP1, AZI2 | NAMPT 832/4885L3MBTL1 4674/4885HDAC1 2457/4885 |
| US-20110245236-A1 | Substituted Benzo-Pyrido-Triazolo-Diazepine Compounds | BRD4, PDXK, THPO | NAMPT 426/4885L3MBTL1 4506/4885HDAC1 444/4885 |
| US-20210371419-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | FN1, BMP1, AZI2 | NAMPT 832/4885L3MBTL1 4674/4885HDAC1 2457/4885 |
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | FN1, BMP1, AZI2 | NAMPT 832/4885L3MBTL1 4674/4885HDAC1 2457/4885 |
| US-12103928-B2 | Processes for preparing a diazabicyclooctane compound | FN1, BMP1, AZI2 | NAMPT 832/4885L3MBTL1 4674/4885HDAC1 2457/4885 |
| US-20250163049-A1 | FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS USP1 INHIBITORS | USP1, USP2, SUMO1 | NAMPT 4125/4885L3MBTL1 1682/4885HDAC1 111/4885 |
| US-11117896-B2 | Processes for preparing a diazabicyclooctane compound | FN1, BMP1, AZI2 | NAMPT 832/4885L3MBTL1 4674/4885HDAC1 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.