Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24270344 | 0.85 | ESR1 (0.41) | PPARGLMNASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL27199273 | 0.80 | HTR1D (0.38) | PPARGMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30803777 | 0.80 | HTR1D (0.38) | PPARGMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24270320 | 0.80 | S1PR1 (0.32) | — | |
| SCHEMBL24270276 | 0.79 | PPARG (0.32) | PPARG | |
| SCHEMBL24270268 | 0.77 | KIF11 (0.47) | — | |
| SCHEMBL29625625 | 0.75 | KIF11 (0.38) | PPARGNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL22588745 | 0.74 | HTR1D (0.37) | MAPTRAB9A | |
| SCHEMBL25847216 | 0.74 | ESR1 (0.40) | PPARGSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL26439701 | 0.73 | PGR (0.39) | PPARGMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074616-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2022-04-14 | — | — | WO | disclosed |